DataBase Content
Product Name | Source | Potential target | Reference | Pubchem | Pubchem Structure |
---|---|---|---|---|---|
Anisotine | SARS-CoV-2 MPRO | Kar et al, 2020 | 442884 | ||
Adhatodine | SARS-CoV-2 MPRO | Kar et al, 2020 | 5316460 | ||
(-)-asperlicin C | 3CLpro inhibitor | Joshi et al, 2020 | 146429 | ||
6- Acetonyldihydrochelerythrine | RdRp inhibitor | Pandeya et al, 2020 | 443700 | ||
Adlumidine | TMPRSS2 inhibitor | Vivek-Ananth et al, 2020 | 120734 | ||
Ajmalicine | Blocking the Nsp15 | Kumar et al, 2020 | 441975 | ||
Allocryptopine | RdRp inhibitor | Pandeya et al, 2020 | 98570 | ||
Alloyohimbine | 3CLpro inhibitor | Gurung et al, 2020 | 120716 | ||
Amaranthin | 3CLpro inhibitor | Qamar et al, 2020 | 6325284 | ||
Anisotine | Mpro inhibitor | Ghosh et al, 2021 | 442884 | ||
Asparagamine A | 3CLpro inhibitor | Gurung et al, 2020 | Notfound | ||
Berbamine | Blocking the E proteins | Gao et al, 2020 | 275182 | ||
Berbamine derivative (BE33) | Blocking the E proteins | Xia et al, 2021 | Notfound | ||
Berberine | 3CLPro inhibitor | Chowdhury, 2020 | 2353 | ||
Berbamine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 275182 | ||
Berberrubine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 72703 | ||
Biscryptolepine | SARS-CoV-2 RdRp | Borquaye et al, 2020 | 10457065 | ||
Cadambine | 3CLPro inhibitor | Yepes-Perez et al, 2020 | 21723831 | ||
Caffeine | Blocking the ACE2 | Mohammadi et al, 2020 | 2519 | ||
Chrysopentamine | 3CLPro inhibitor | Gyebi et al, 2020 | 49799721 | ||
Crambescidin 786 | Blocking the Nsp10 | El-Demerdash et al, 2021 | 132937446 | ||
Crambescidin 826 | Blocking the N proteins | El-Demerdash et al, 2021 | 3011698 | ||
Cryptomisrine | Mpro inhibitor | Borquaye et al, 2020 | 10600127 | ||
Cryptoquindoline | Mpro inhibitor | Gyebi et al, 2020 | 44583948 | ||
Cryptospirolepine | Cryptolepis sanguinolenta (Periplocaceae) | SARS-CoV-2 | Ogunyemi et al, 2020 | 9914081 | |
Coptisine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 72322 | ||
Cepharanthine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 10206 | ||
Cryptoquindoline | SARS-CoV-2 MPRO | Gyebi et al, 2020 | 44583948 | ||
Cryptospirolepine | SARS-CoV-2 MPRO | Gyebi et al, 2020 | 9914081 | ||
Cryptomisrine | SARS-CoV-2 RdRp | Borquaye et al, 2020 | 10600127 | ||
Cepharanthine | Blocking the expression of S proteins | Kim et al, 2019 | 10206 | ||
Conessine | Mpro inhibitor | Shen et al, 2019 | 441082 | ||
3α,17α-Cinchophylline | Cathepsin L inhibitor | Vivek-Ananth et al, 2020 | Notfound | ||
Dioncophylline B | Triphyophyllum peltatum (Dioncophyllaceae) | SARS-CoV-2 | Ogunyemi et al, 2020 | 178558 | |
Dicentrine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 101300 | ||
Dihydroergotamine | 3CLPro inhibitor | Gul et al, 2020 | 10531 | ||
Emetine | Mpro inhibitor | Choy et al, 2020 | 10219 | ||
Epiisopiloturine | Mpro inhibitor | de Sa et al, 2021 | 155306 | ||
Ergometrine | Mpro inhibitor | Mostafa et al, 2021 | 443884 | ||
Ergotamine | 3CLPro inhibitor | Gul et al, 2020 | 8223 | ||
Fangchinoline | Blocking the expression of S proteins | Kim et al, 2019 | 73481 | ||
Fumigatoside E | Blocking the ACE2 | Youssef et al, 2021 | 146684188 | ||
Fangchinoline | SARS-CoV nucleic acid intercalation | Wink, 2007 | 73481 | ||
Harmine | Mpro inhibitor | Shen et al, 2019 | 5280953 | ||
Hernandezine | Blocking the calcium transition | He et al, 2021 | 72343 | ||
10- Hydroxyusamb arensine | SARS-CoV-2 MPRO | Gyebi et al, 2020 | Notfound | ||
Homoharringtonine | Blocking the S proteins | Choy et al, 2020 | 285033 | ||
10- Hydroxyusamb arensine | Strychnos usambarensis (Loganiaceae) | SARS-CoV-2 | Ogunyemi et al, 2020 | 10433813 | |
18-Hydroxy-3-epialphayohimbine | 3CLPro inhibitor | Gurung et al, 2020 | Notfound | ||
Indican | Mpro inhibitor | Narkhede et al, 2020 | 441564 | ||
Indigo | Mpro inhibitor | Narkhede et al, 2020 | 10215 | ||
Indirubin | Mpro inhibitor | Narkhede et al, 2020 | 10177 | ||
Jatrorrhizine | SARS-CoV nucleic acid intercalation | Wink, 2007 | 72323 | ||
Lycorine | Mpro inhibitor | Li et al, 2020 | 72378 | ||
7- Methoxycryptopleurine | Blocking the S proteins | yang et al, 2010 | 11848155 | ||
Neferine | Decreasing the levels of relative viral RNA | He et al, 2021 | 159654 | ||
Nicotine | Blocking the ACE2 | Mohammadi et al, 2020 | 89594 | ||
Norquinadoline A | Blocking the ACE2 | Ismail et al, 2021 | 71725622 | ||
Noscapine | Mpro inhibitor | Kumar et al, 2020 | 275196 | ||
Noscapine 23B | Mpro inhibitor | Kumar et al, 2020 | Notfound | ||
Oxysophoridine | Nucleotide biosynthesis inhibitor | Zhang et al, 2020 | 114850 | ||
Oriciacridone F | 3CLPro inhibitor | Joshi et al, 2020 | 11685925 | ||
Oxoturkiyenine | Cathepsin L inhibitor | Vivek-Ananth et al, 2020 | 189308 | ||
Palmatine | 3CLPro inhibitor | Joshi et al, 2020 | 19009 | ||
Papaverine | Mpro inhibitor | Mostafa et al, 2021 | 4680 | ||
Piperine | Blocking the ACE2 | Maurya et al, 2020 | 638024 | ||
Protopine | RdRp inhibitor | Pandeya et al, 2020 | 4970 | ||
Pseudojervine | Blocking the ACE2 | Cheng et al, 2020 | 16398499 | ||
Quinine | Mpro inhibitor (in silico study) | Gendrot et al, 2020 | 3034034 | ||
Qingdainone | Inhibitors of TMPRSS2 | Vivek-Ananth et al, 2020 | 3035728 | ||
Reserpine | Blocking the Nsp15 | Kumar et al, 2020 | 5770 | ||
Sanguinarine | 3CLPro inhibitor | Joshi et al, 2020 | 5154 | ||
Solanidine | Blocking the S proteins | Ubani et al, 2020 | 65727 | ||
Sophaline D | Mpro inhibitor | Garg and Roy 2020 | 132991317 | ||
Sophoridine | Mpro inhibitor | Gurung et al, 2020 | 165549 | ||
Speciophylline | 3CLPro inhibitor | Yepes-Perez et al, 2020 | 168985 | ||
Strychnopentamine | Strychnos usambarensis (Loganiaceae) | SARS-CoV-2 | Ogunyemi et al, 2020 | 6712640 | |
Socryptolepine | Cryptolepis sanguinolenta (Periplocaceae) | SARS-CoV-2 | Ogunyemi et al, 2020 | Notfound | |
Schizanthine Z | SARS-CoV-2 PLPRO | Alfaro et al, 2020 | 70698234 | ||
Tetrandrine | Blocking the expression of S proteins | Shen et al, 2019 | 73078 | ||
Tylophorine | Blocking the S proteins | Li et al, 2013 | 92114 | ||
Tabersonine | 3CLPro inhibitor | Joshi et al, 2020 | 20485 | ||
Taspine | Blocking the Nsp15 | Kumar et al, 2020 | 215159 | ||
Tetrahydropalmatine | 3CLPro inhibitor | Chowdhury, 2020 | 5417 | ||
Thalimonine | Mpro inhibitor | Garg and Roy 2020 | 10893946 | ||
Thebaine | Blocking the ACE2 | Maurya et al, 2020 | 5324289 | ||
Tryptanthrine | Mpro inhibitor | Narkhede et al, 2020 | 73549 | ||
Vincapusine | 3CLPro inhibitor | Gurung et al, 2020 | 11646359 | ||
Vasicoline | SARS-CoV-2 MPRO | Kar et al, 2020 | 626005 | ||
Vasicine | SARS-CoV-2 MPRO | Kar et al, 2020 | 667496 |