tablysin-15


Organism:Tabanus yao
Taxonomy:https://www.uniprot.org/taxonomy/485572
Uniprot ID:F8QQG5
PDB ID:3U3N
Mass:28.22
Length:255
Sequence:F8QQG5.fasta


LigandActivitiesIC50Cell linesReferences
Fibronectin, fibrinogen,vitronectininhibits platelet aggregation and angiogenesis.exhibits high affinity binding for platelet AlphaIIbBeta3 and endothelial cell AlphaVBeta3 integrins, it blocks endothelial cell adhesion to vitronectin (IC50 ~1 nM) and marginally to fibronectin (IC50 ~1 μM), inhibits aggregation induced by collagen, ADP and convulxin, and prevents static platelet adhesion to immobilised fibrinogen Human platelet-rich plasma (PRP)https://pubmed.ncbi.nlm.nih.gov/21475772