tablysin-15
Organism: | Tabanus yao |
Taxonomy: | https://www.uniprot.org/taxonomy/485572 |
Uniprot ID: | F8QQG5 |
PDB ID: | 3U3N |
Mass: | 28.22 |
Length: | 255 |
Sequence: | F8QQG5.fasta |
Ligand | Activities | IC50 | Cell lines | References |
Fibronectin, fibrinogen,vitronectin | inhibits platelet aggregation and angiogenesis.exhibits high affinity binding for platelet AlphaIIbBeta3 and endothelial cell AlphaVBeta3 integrins, it blocks endothelial cell adhesion to vitronectin (IC50 ~1 nM) and marginally to fibronectin (IC50 ~1 μM), inhibits aggregation induced by collagen, ADP and convulxin, and prevents static platelet adhesion to immobilised fibrinogen | Human platelet-rich plasma (PRP) | https://pubmed.ncbi.nlm.nih.gov/21475772 |