eristostatin


Organism:Eristicophis macmahoni
Taxonomy:https://www.uniprot.org/taxonomy/110227
Uniprot ID:P0C6S4
PDB ID:
Mass:5.511
Length:49
Sequence:P0C6S4.fasta


LigandActivitiesIC50Cell linesReferences
VCAM-1, VEGF-A, OPN, Tenascin-C, angiostatin, tTG, factor XIIIa potent inhibitor of ADP-induced platelet aggregation. a potent inhibitor of human and murine melanoma metastases in mouse model systems, also due to the inhibition of binding between the alpha-4/beta-1 integrin and the vascular cell adhesion protein VCAM1.inhibits cell migration on fibronectin, but not that on collagen IV or laminin.7-8 Nmmouse model systemshttps://pubmed.ncbi.nlm.nih.gov/7641809 https://pubmed.ncbi.nlm.nih.gov/8042985 https://pubmed.ncbi.nlm.nih.gov/7538018 https://pubmed.ncbi.nlm.nih.gov/9457071 https://pubmed.ncbi.nlm.nih.gov/7549046 https://pubmed.ncbi.nlm.nih.gov/17316731