disagregin


Organism:Ornithodoros moubata
Taxonomy:https://www.uniprot.org/taxonomy/6938
Uniprot ID:P36235
PDB ID:
Mass:6.962
Length:60
Sequence:P36235.fasta


LigandActivitiesIC50Cell linesReferences
Fibronectin, fibrinogenInhibits fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex. Acts by binding to the glycoprotein IIb-IIIa receptor on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. IC50 = 104 +/- 17 NmHuman blood https://pubmed.ncbi.nlm.nih.gov/8120028 https://pubmed.ncbi.nlm.nih.gov/9434779