barbourin
Organism: | Sistrurus miliarius barbouri |
Taxonomy: | https://www.uniprot.org/taxonomy/8759 |
Uniprot ID: | P22827 |
PDB ID: | |
Mass: | 7.701 |
Length: | 73 |
Sequence: | P22827.fasta |
Ligand | Activities | IC50 | Cell lines | References |
fibronectin, vitronectin, fibrinogen, VWF, TSP | Inhibitor of ligand binding to the integrins alpha-IIb/beta-3 Competition with fibrinogen for the RGD recognition sites on the alpha-IIb/beta-3 integrin results in the inhibition of platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. | 309 ±128nM | Platelet rich plasma | https://pubmed.ncbi.nlm.nih.gov/7617961 https://pubmed.ncbi.nlm.nih.gov/10815769 https://pubmed.ncbi.nlm.nih.gov/2033037 |