accutin

Organism:Deinagkistrodon acutus
Taxonomy:https://www.uniprot.org/taxonomy/36307
Uniprot ID:P0DM77
PDB ID:
Mass:5.333
Length:48
Sequence:P0DM77.fasta


LigandActivitiesIC50Cell linesReferences
Fibronectin, vitronectin, fibrinogen, VWF, TSP, FGF-2Inhibit human platelet aggregation induced by ADP, collagen, thrombin or the thromboxane analog U46619 in platelet suspension.inhibits angiogenesis in vivo and in vitro by blocking integrin alpha-V/beta-3 66-267 nM. human umbilical vein endothelial cells (HUVECs)https://pubmed.ncbi.nlm.nih.gov/9838213 https://pubmed.ncbi.nlm.nih.gov/9787163