Rhodostomin(Kistrin)


Organism:Calloselasma rhodostoma
Taxonomy:https://www.uniprot.org/taxonomy/8717
Uniprot ID:P30403
PDB ID:3UCI
Mass:7847.85
Length:72
Sequence:P30403.fasta


LigandActivitiesIC50Cell linesReferences
fibronectin, vitronectin, fibrinogen, VWF, TSP inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors alpha-IIb/beta-3inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells.200 nMSaos-2 tumour cell-induced platelet aggregation (TCIPA)https://pubmed.ncbi.nlm.nih.gov/7841039