Rhodostomin(Kistrin)
Organism: | Calloselasma rhodostoma |
Taxonomy: | https://www.uniprot.org/taxonomy/8717 |
Uniprot ID: | P30403 |
PDB ID: | 3UCI |
Mass: | 7847.85 |
Length: | 72 |
Sequence: | P30403.fasta |
Ligand | Activities | IC50 | Cell lines | References |
fibronectin, vitronectin, fibrinogen, VWF, TSP | inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors alpha-IIb/beta-3inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells. | 200 nM | Saos-2 tumour cell-induced platelet aggregation (TCIPA) | https://pubmed.ncbi.nlm.nih.gov/7841039 |