EC3
Organism: | Echis carinatus |
Taxonomy: | https://www.uniprot.org/taxonomy/9606 |
Uniprot ID: | P81631 |
PDB ID: | |
Mass: | 7.424 |
Length: | 67 |
Sequence: | P81631.fasta |
Ligand | Activities | IC50 | Cell lines | References |
Fibronectin, VCAM, MAdCAM(VCAM-1) (MadCAM-1)Fibronectin | Calcium-dependent cell-adhesion protein inhibits human and murine alpha4 integrin and attenuates lymphocyte infiltration of Langerhans islets in pancreas and salivary glands in nonobese diabetic mice. EC3inhibited adhesion of cells expressing alpha4beta1 and alpha4beta7 integrins to natural ligands | IC50 = 150 nM | K562 Cells | https://pubmed.ncbi.nlm.nih.gov/10623633 https://pubmed.ncbi.nlm.nih.gov/10212222 |