Bisba-01


Organism:Bothrops alternatus
Taxonomy:https://www.uniprot.org/taxonomy/64174
Uniprot ID:Q801Z4
PDB ID:
Mass:8.236
Length:78
Sequence:Q801Z4.fasta


LigandActivitiesIC50Cell linesReferences
fibronectin, vitronectin, fibrinogen, VWF, TSPinhibits platelet aggregation induced by ADP, thrombin, and collagen, abolishes and reverses dynamic platelet recruitment to immobilized fibrinogen.inhibits the adhesion of ITGAV/ITGB3-expressing human microvascular endothelial cell line and murine melanoma cell line to vitronectin.inhibits their proliferation without direct cell toxicity,inhibits tumor cell migration in vitro555 nM human microvascular endothelial cell linemurine melanoma cell linehttps://pubmed.ncbi.nlm.nih.gov/17952617 https://pubmed.ncbi.nlm.nih.gov/18508682 https://pubmed.ncbi.nlm.nih.gov/22561350